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StudyLTCOVID.com

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A "Quick Impressions" CONTROL participant gets (along with everything else in the box!), two envelopes.

The CONTROL group provides comparisons with results of participants carrying out an intervention with red (660-670nm) and near-infrared (830-850nm) light. 

The basis of the "Quick Impressions" protocol is to do some tests, carry out a 10 day intervention with light (photobiomodulation) and repeat the tests, looking for any changes.

Clearly, those in this CONTROL group do not carry out the intervention with light.

But they do carry out certain tests that provide comparisons with the results from the intervention group.

But which tests? And carried out how? And using what equipment?

This is fully introduced in a PDF document found at this link. Also, as a WORD document.

The document is also included in each "Day 0" and "Day 11" envelope found in the box of materials provided to a CONTROL subgroup participant.

And to simplify your entry as a participant in the "Quick Impressions" study protocol as a Control subject, start by completing this survey which is pretty much self-explanatory. 

DAY 0 and DAY 11.

The above linked to introduction (4 pages) should be adequate to permit below, an efficient presentation of required links for reporting each test done. They are reported using different surveys for each of the two days (0 or 11). The aim is to avoid mixing results.

The CONTROL subgroup will be doing:

• • • Test 1 - Signs and Symptoms Frequency
    • Test 2 - Trail Making Test A & B
    • Test 3 - Mental Status Exam
    • Test 4 - Visual Acuity Test (OMITTED in the CONTROL Subgroup)
    • Test 5 - Attention & Reaction Time Test
    • Test 6 - 6 Minute Walking Test (6'WT) with
      • • Vital Signs (VS) at "Pre", Time 0, 5, 10, 15 minutes (Vital Signs Sheet included)
          • VS = oral temp with infrared thermometer, spO2 with pulse oximeter, BP systolic, BP diastolic & pulse. 
        • Finger stick and peripheral smear preparation at "Pre" and again at 15 minutes after the end of the 6'WT. 
        • In envelope "Day 0" is a form for writing down Vital Signs measurements. There are enough lines on the form to do "Day 11" as well. Eventually, you can scan or photograph your completed forms, and I will transfer your measurements to the database we use for that. 
        • Even easier: use this online survey to report your Vital Signs for Day 0, Day 11, or for both days.
        • Again, use the equipment provided even if you have better ! 
        • Again, use the Vital Signs Stand to keep the blood pressure cuff at a constant relationship with your heart. Not complicated, and a page to explain the "How To's" is on this site at this page.

NOT in the envelope but given here are copies of all the links to these and as already found in the Day 0 introductory article.

The surveys ask for your Study ID#. For those in the CONTROL group, that looks like this:

QIc-WJO-1950  which means Quick Impressions control - initials or a pseudonym - Year of Birth. Remember the "c" after the "QI". Those not in the intervention group use only QI-xx-19xx. So the "c" should allow correct identification of participants in the Control subgroup.

Certain survey questions may address subjects for those with "long-term" COVID-19 who are also doing the intervention with light. If in the Control group, simply skip these.

Here are those links once again: Important to recall that even though the tests on Day 0  and Day 11 are usually identical, their results are reported online at different links. So first in what follows, is for ...

DAY 0:

• Test 1 - Signs and Symptoms Frequency. Here is the link to take TEST 1 now on Day 0.
• Test 2 - Trail Making Test A & B 
  • Print forms if needed: TMT Part A and TMT Part B They are also included in each "Day 0" and "Day 11" envelope that came in your box.
  • Place your results online at this link.
• Test 3 - Mental Status Exam Here is the link to take the MSE online on Day 0.
• Test 4 - Visual Acuity - skip this if in the Control group.
• Test 5 - Attention & Reaction Time Test - You need the provided stopwatch. The video that explains the test, also administers it. It is found on Youtube at this link. https://youtu.be/LwWZdhICf0o  Your responses (there are only two to give) are given online at https://www.surveymonkey.com/r/Z78C5P2 or click this link.
• Test 6 - 6 Minute Walking Test, with tests before and after.
  • Vital Signs using supplied equipment at rest ("Pre") then at 0, 5, 10, 15 minutes.
    • You may have the required equipment (or better !) but we like the idea that everyone is using the same equipment for Vital Signs measurements. Especially, for the blood pressure measurements, using the supplied stand keeps things very consistent. Report your results using the supplied form, with a picture emailed to Vitals@StudyLTCovid.com, or perhaps faster: this online survey format for Vital Signs.
    • One finger stick and preparation of a blood smear at "Pre" (at rest before exercise).
      • This link presents a video explaining in great detail how to do the peripheral smear. That video is also embedded at the bottom of this page for convenience.
    • One finger stick and preparation of a blood smear at 15 minutes after exercise.
      • Both are sent as soon as possible after their preparation to the address already written on the 'Day 0' envelope supplied in the box. Wrap the glass slides in the 3 "click together" plastic shipping boxes (top one is empty), wrapped as you received them. They're labelled to avoid error.

How could the 6 Minute Walking Test get messed up?

• • • If you're not marching at the same pace as other participants.
    • If you have a treadmill, but don't have the speeds/ durations and when they change listed in front of you on the treadmill. (see below)
    • If you don't have a CD player (they're old fashioned now, didn't you know?) to play the CD that is in your box that was sent you.
    • You go up and down steps to prove something. Don't. Just stay on the same level.
    • You forget that after the 6 minutes are done, you take Vital Signs at 0 (immediately!), 5, 10 and 15 minutes. (Example: You got a little exercise for 6 minutes. Then you went and made some coffee and called a friend. The study gets no data).
    • You never reported the your results. Use this online survey to report your Vital Signs.
    • Some other unforeseen tragedy or disaster. 

So here is a link that will play the 6 Minute Walking Test through your computer's speakers.

While it gives prompts in English, following the drum beat gives the correct pace and changes in speed. This recording also refers to final Vital Signs at 0, 5, 10 minutes. But for those in the "Quick Impressions" protocol and Controls, we add 15 minutes, at rest after marching around.

And if you have a treadmill, and you (or even better someone else) can make the speed increases at the appropriate times, below are those intervals. The pace is rather slow, especially for an endurance athlete. But with "long-term" COVID-19 aboard, anything is possible. Remember, if you feel like passing out, sit down and stop all this nonsense! (But do quickly take your Vital Signs if you're still conscious !).

Once again, the Protocol for CONTROLS is explained here if you'd like to print it.

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Next, links for ...

DAY 11:

As noted above, the tests are identical, but the results are reported using a day-specific link.

In the CONTROL group? Remember the "c" in your Study ID# (QIc-Joe-1984).

• Test 1 - Signs and Symptoms Frequency. Here is the link to take TEST 1 now on Day 11.
• Test 2 - Trail Making Test A & B 
  • Print forms if needed: TMT Part A and TMT Part B (I placed these in your Day 11 envelope, just in case). Remember to have the stopwatch handy to time start to finish.
  • Place your results online at this link on Day 11.
• Test 3 - Mental Status Exam Here is the link to take the MSE onlinehttps://www.surveymonkey.com/r/76N2VWT on Day 11.
• Test 4 - Visual Acuity - Not done by the CONTROL group.
• Test 5 - Attention & Reaction Time Test - the video that explains the test, also administers it. The test for Day 11 is found on Youtube at this link. https://youtu.be/ffedNoOBFRk
• If you prefer, it is embedded below for direct use on Day 11.

• Your responses to the test (there are only two to give) are collected online at https://www.surveymonkey.com/r/J27WSPB or click this link.
• Test 6 - 6 Minute Walking Test, (6'WT) with tests before and after.
  • Vital Signs using supplied equipment at rest ("Pre") then at 0, 5, 10, 15 minutes.
    • You may have the required equipment (or better !) but we like the idea that everyone is using the same equipment. Especially, for blood pressure measurements, using the supplied stand keeps things very consistent. 
    • Send in your Vital Signs Results by online survey or a picture of your completed form to Vitals@StudyLTCovid.com
    • One finger stick and preparation of a blood smear at "Pre" (at rest before exercise)
    • One finger stick and preparation of a blood smear at 15 minutes after exercise.
      • Both are sent as soon as possible after their preparation to the address already written on the 'Day 11' envelope supplied in the box. Wrap the glass slides in the 3 "click together" plastic shipping boxes, wrapped as you received them. They're labelled to avoid error.
• Day 11, Test 7 - That is a final survey to see how you and photobiomodulation (PBM) were able to get a long.  That may seem silly, since in the CONTROL Group no intervention with light was carried out. Please take this anyway to see how much your last 10 days may have generated some responses, even without the light. Here is the link to the survey on your NON-intervention over 10 days with PBM.

The present page is found on the StudyLTCovid.com site at the following link:

https://www.studyltcovid.com/quick-impressions-day-0-and-day-11-envelopes-1

As mentioned, a copy of this page will be placed in both the Day 0 and Day 11 envelopes that you received. This paper page doesn't have functioning links of course!

So use this as a reminder, but go to the actual article online for the convenience of having everything for Tests and Results for the CONTROL subgroup be a simple click away.

And if you find that a link is broken or in error, please let us know. 

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The Peripheral Smear:

How to do it and what to do with the slides you prepare:

If you are fixing your slides at home after air-drying them, here is a very brief summary of how to do that. 

If not done yet, have a look at this short survey to get you enrolled as a participant.

This helps to make things easier for you, and more manageable for us. Have a look. You'll understand we're sure. It saves us (and you) from asking and answering the same questions over and over again.

If you'd like a QR Code for access to this survey, here's one:

It will take you directly from your Smart Phone or PC to the survey to quickly register as a participant. Participants get registered. Whether as an LTC intervention subject, or a CONTROL, Participants Get Registered. Why? Well as we wrote above but you might have skipped over:

1. This helps to make things easier for you, and more manageable for us.
2. It saves us (and you) from asking and answering the same questions over and over again.

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